Acid Mouthwash: In 30 patients receiving anticoagulants, a dual-blind randomization analysis was performed to determine the clinical hemostatic effect of the tranexamic acid mouthwash.
Surgical procedure was performed with a decrease in the anticoagulant therapy level within the control group and no improvements in the anticoagulant therapy level within the tranexamic acid group.
Following extraction, the operating area was irrigated in 15 patients whose anticoagulant therapy was not prevented by a solution of 5% tranexamic acid and in 15 patients for whom anticoagulant therapy was decreased by a placebo solution.
Patients were advised for 2 minutes four times a day for seven days to rinse their mouths with 10 ml of the assigned solution.
In the occurrence of bleeding after oral surgery there was no substantial difference between the two treatment classes.
We conclude that before oral surgery, anticoagulant treatment does not need to be removed if local antifibrinolytic therapy is developed.